Fold recognition
Recognize (predict and identify) known protein structural domains or folds in protein sequence(s) which (typically) are not accompanied by any significant sequence similarity to know structures.
Synonyms: Protein domain prediction, Domain prediction, Protein fold prediction, Fold prediction, Protein fold recognition
Term info
Subsets
operations, edam
Created in
beta12orEarlier
comment
Methods use some type of mapping between sequence and fold, for example secondary structure prediction and alignment, profile comparison, sequence properties, homologous sequence search, kernel machines etc. Domains and folds might be taken from SCOP or CATH.