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Gene-set enrichment analysis

^ http://edamontology.org/operation_2436

Identify classes of genes or proteins that are over or under-represented in a large set of genes or proteins. For example analysis of a set of genes corresponding to a gene expression profile, annotated with Gene Ontology (GO) concepts, where eventual over-/under-representation of certain GO concept within the studied set of genes is revealed.

Synonyms: GSEA, Gene set analysis, Functional enrichment analysis, Gene-set over-represenation analysis

Term info

Subsets

operations, edam

Created in

beta12orEarlier

comment

"Gene set analysis" (often used interchangeably or in an overlapping sense with "gene-set enrichment analysis") refers to the functional analysis (term enrichment) of a differentially expressed set of genes, rather than all genes analysed., The Gene Ontology (GO) is typically used, the input is a set of Gene IDs, and the output of the analysis is typically a ranked list of GO concepts, each associated with a p-value.

hasBroadSynonym

Gene set testing

hasRelatedSynonym

Gene Ontology term enrichment, GO-term enrichment, Gene Ontology concept enrichment

seeAlso

https://en.wikipedia.org/wiki/Gene_set_enrichment_analysis, https://en.wikipedia.org/wiki/Gene_Ontology_Term_Enrichment