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Bisulfite mapping

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The mapping of methylation sites in a DNA (genome) sequence. Typically, the mapping of high-throughput bisulfite reads to the reference genome.

Synonyms: Bisulfite read mapping, Bisulfite sequence mapping, Bisulfite sequence alignment

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Bisulfite mapping follows high-throughput sequencing of DNA which has undergone bisulfite treatment followed by PCR amplification; unmethylated cytosines are specifically converted to thymine, allowing the methylation status of cytosine in the DNA to be detected.

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