thrombin
http://www.ebi.ac.uk/efo/EFO_0003183
Term info
database cross reference
- NCIt:C87773
- OMIM:176930
- DSSTox_Generic_SID:40626
- SNOMEDCT:415715002
- SNOMEDCT:36176003
- MeSH:D013917
definition
Thrombin is a "trypsin-like" serine protease protein that in humans is encoded by the F2 gene.[2][3] Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the stemming of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions.
definition citation
http://en.wikipedia.org/wiki/Thrombin
term editor
Ele Holloway, James Malone, Tomasz Adamusiak