Term info
database cross reference
- OMIM:600044
- CASRN:9014-42-0
- SNOMEDCT:18617001
- DSSTox_Generic_SID:40918
- MeSH:D013926
- NCIt:C20441
definition
Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the THPO gene. Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets.[1]
definition citation
http://en.wikipedia.org/wiki/Thrombopoietin
term editor
Ele Holloway, James Malone, Tomasz Adamusiak