Term info
database cross reference
- DSSTox_CID:40634
- OMIM:191160
- MeSH:D014409
- CASRN:308079-78-9
definition
Tumor necrosis factor (TNF, cachexin or cachectin formerly known as tumor necrosis factor-alpha or TNF-α) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well.
definition citation
http://en.wikipedia.org/wiki/Tumour_necrosis_factor-alpha
has exact synonym
TNF-alpha; tumor necrosis factor
term editor
Ele Holloway, James Malone, Tomasz Adamusiak