JSON

aldosterone

^ http://purl.obolibrary.org/obo/CHEBI_27584

A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.

Synonyms: 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al, aldosterone, ALDOSTERONE, Aldosterone

Term info

database cross reference
  • Beilstein:3224996 (ChemIDplus)
  • CAS:52-39-1 (NIST Chemistry WebBook)
  • Drug_Central:111 (DrugCentral)
  • DrugBank:DB04630
  • LIPID_MAPS_instance:LMST02030026 (LIPID MAPS)
  • PMID:10438974 (Europe PMC)
  • PDBeChem:AS4
  • HMDB:HMDB0000037
  • CAS:52-39-1 (ChemIDplus)
  • Reaxys:3224996 (Reaxys)
  • LINCS:LSM-42770
  • Wikipedia:Aldosterone
  • KEGG:C01780
  • CAS:52-39-1 (KEGG COMPOUND)
Subsets

3_STAR

charge

0

formula

C21H28O5

has related synonym

(11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al, 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al, (+)-aldosterone

has alternative id

CHEBI:40919, CHEBI:22306, CHEBI:2563

has obo namespace

chebi_ontology

id

CHEBI:27584

inchi

InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1

inchikey

PQSUYGKTWSAVDQ-ZVIOFETBSA-N

mass

360.44400

monoisotopicmass

360.19367

smiles

[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C=O)C(=O)CO