neutrophilic myeloblast
http://purl.obolibrary.org/obo/CL_0000042
A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor. [ http://openisbn.com/search.php?q=0721601464&isbn=1/ http://www.ncbi.nlm.nih.gov/pubmed/15514007 GOC:add http://www.ncbi.nlm.nih.gov/pubmed/12560239 ]
Term info
These cells are CD11b-negative, CD15-negative, CD16-negative, CD35-negative, CD49d-positive, CD68-positive, lactotransferrin-negative, and fMLP receptor-negative. They are found in the Band 3 fraction.
neutrophilic granuloblast
Term relations
- myeloblast and has part some transcription factor PU.1 and has part some CCAAT/enhancer-binding protein alpha and has part some erythroid transcription factor and has part some myb proto-oncogene protein and has part some runt-related transcription factor 1 and capable of some neutrophil differentiation
- myeloblast
- neutrophil progenitor cell
- protein-containing material entity
- has part some myb proto-oncogene protein
- has part some runt-related transcription factor 1
- has part some transcription factor PU.1
- has part some CCAAT/enhancer-binding protein alpha
- has part some erythroid transcription factor
- develops from some neutrophil progenitor cell