mature basophil
http://purl.obolibrary.org/obo/CL_0000043
A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. [ http://www.ncbi.nlm.nih.gov/pubmed/18466030 GOC:dsd http://openisbn.com/search.php?q=0721601464&isbn=1/ GOC:add http://www.cap.org http://www.ncbi.nlm.nih.gov/pubmed/19231594 http://www.ncbi.nlm.nih.gov/pubmed/20837449 GOC:tfm ]
Synonyms: mature basophil leucocyte, mature basophil leukocyte
Term info
- CALOHA:TS-0688
- BTO:0001026
Mature basophils are also capable of producing IL-3, IL-5, IL-6, IL-8, IL-13, IL-25, CCL22, tslp, vegf, and LTC4.
polymorphonuclear leucocyte, polymorphonuclear leukocyte
Term relations
- basophil and has part some (
nucleus and
bearer of some lobed) and capable of some histamine production involved in inflammatory response and capable of some serotonin production involved in inflammatory response and capable of some positive regulation of type 2 immune response and capable of some blood circulation and capable of some interleukin-13 production and capable of some interleukin-4 production and capable of some positive regulation of isotype switching to IgE isotypes
- histamine secreting cell
- basophil
- capable of some interleukin-4 production
- has part some (
nucleus and
bearer of some lobed) - capable of some histamine production involved in inflammatory response
- capable of some positive regulation of type 2 immune response
- capable of some interleukin-13 production
- capable of some positive regulation of isotype switching to IgE isotypes
- capable of some serotonin production involved in inflammatory response
- develops from some band form basophil