common lymphoid progenitor
A oligopotent progenitor cell committed to the lymphoid lineage. [ http://www.ncbi.nlm.nih.gov/pubmed/10407577 GOC:add http://www.ncbi.nlm.nih.gov/pubmed/16551251 GOC:tfm GOC:dsd ]
Synonyms: CLP, common lymphocyte precursor, common lymphoid precursor, common lymphocyte progenitor
Term info
human_reference_atlas
CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.
committed lymphopoietic stem cell, lymphopoietic stem cell, ELP, early lymphocyte progenitor, lymphoid stem cell
CL:0000044
http://purl.obolibrary.org/obo/NCBITaxon_9606
Term relations
- hematopoietic oligopotent progenitor cell
- progenitor cell
- capable of some lymphocyte differentiation