primary dermal fibroblast, mouse embryonic fibroblast

A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms., A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules., A large, flat, oval cell found in connective tissue and responsible for the formation of fibers., These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.

BTO:0000452, NIFSTD:nlx_cell_20090201, CL:0000057

cell

http://purl.obolibrary.org/obo/uberon.owl, http://purl.obolibrary.org/obo/cl.owl

Fibroblast

http://purl.obolibrary.org/obo/NCBITaxon_9606

URI: http://www.ebi.ac.uk/cellline#fibroblast, EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000496

Tomasz Adamusiak, James Malone

• fibroblast migration

• skeletal ligament
• loose mesenchyme tissue
• dense mesenchyme tissue
• outer fibrous layer of periosteum
• regular connective tissue
• renal cortex interstitium

• dermal papilla

• fibroblast proliferation

• fibroblast apoptotic process

• fibroblast activation

• fibrocyte