T-helper 1 cell
http://purl.obolibrary.org/obo/CL_0000545
A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. [ http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/20303875 http://www.ncbi.nlm.nih.gov/pubmed/22343568 GOC:add GOC:pam http://www.ncbi.nlm.nih.gov/pubmed/19375293 GOC:tfm ]
Synonyms: T(H)-1 cell, Th1 CD4+ T cell, T helper cells type 1, Th1 T-cell, Th1 T-lymphocyte, helper T cell type 1, Th1 T lymphocyte, Th1 cell, Th1 T cell
Term info
- BTO:0001678
- FMA:84382
human_reference_atlas
This cell type is compatible with the HIPC Lyoplate markers for 'Th1 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 1 T cells.
http://purl.obolibrary.org/obo/NCBITaxon_9606
Term relations
- CD4-positive helper T cell and has part some T-box transcription factor TBX21 and lacks_plasma_membrane_part some C-C chemokine receptor type 6 and has plasma membrane part some C-X-C chemokine receptor type 3 and capable of some type II interferon production