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pericyte

^ http://purl.obolibrary.org/obo/CL_0000669

An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. [ GOC:tfm http://www.ncbi.nlm.nih.gov/pubmed/17986482 GOC:dsd http://www.ncbi.nlm.nih.gov/pubmed/16807374 http://openisbn.com/search.php?q=0721662544&isbn=1/ MESH:D020286 http://www.ncbi.nlm.nih.gov/pubmed/20024907 ]

Synonyms: ARC, cell of Rouget, adventitial reticular cell, pericyte of Rouget, pericyte cell

Term info

database cross reference
  • BTO:0002441
  • FMA:63174
Subsets

human_reference_atlas

comment

Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A.

has related synonym

adventitial cell

has alternative id

CL:0000184

prefLabel

Pericyte

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606