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eosinophil

^ http://purl.obolibrary.org/obo/CL_0000771


Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. [ GOC:amm http://www.ncbi.nlm.nih.gov/sites/entrez?db=pmc&cmd=search&term=PMC2626675 GOC:tfm http://openisbn.com/search.php?q=0721601464&isbn=1/ http://www.ncbi.nlm.nih.gov/pubmed/1662676 http://www.ncbi.nlm.nih.gov/pubmed/10914487 GOC:dsd GOC:add ]

Synonyms: eosinophilic leukocyte, eosinocyte, eosinophilic leucocyte, eosinophilic granulocyte

Term info

database cross reference
  • BTO:0000399
  • MESH:D004804
  • FMA:62861
  • CALOHA:TS-0279
Subsets

human_reference_atlas

comment

Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte.

has broad synonym

polymorphonuclear leucocyte, polymorphonuclear leukocyte

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606