JSON

CD8-positive, alpha-beta cytotoxic T cell

^ http://purl.obolibrary.org/obo/CL_0000794


A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive. [ GOC:tfm http://openisbn.com/search.php?q=0781735149&isbn=1/ http://purl.obolibrary.org/obo/go/references/0000031 GOC:pam GOC:add ]

Synonyms: CD8-positive, alpha-beta cytotoxic T lymphocyte, CD8-positive, alpha-beta cytotoxic T-lymphocyte, CD8-positive, alpha-beta cytotoxic T-cell

Term info

database cross reference
  • FMA:70573
  • CALOHA:TS-0190
Subsets

human_reference_atlas

comment

Note that while T cells of this subset are loosely referred to 'cytotoxic T cells,' as many other T cell types, including CD4-positive, alpha-beta T cells and gamma-delta T cells exhibit cytotoxicity in vitro and in vivo.

has broad synonym

cytotoxic T cell, cytotoxic T lymphocyte, killer T-cell, killer T-lymphocyte, killer T lymphocyte, cytotoxic T-cell, cytotoxic T-lymphocyte, killer T cell

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606