classical monocyte
http://purl.obolibrary.org/obo/CL_0000860
A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes. [ http://www.ncbi.nlm.nih.gov/pubmed/16322748 http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/20870168 GOC:add http://www.ncbi.nlm.nih.gov/pubmed/20628149 http://www.ncbi.nlm.nih.gov/pubmed/18303997 ]
Synonyms: inflammatory monocyte
Term info
human_reference_atlas
Markers: CCR2+CXCCR1<low> (human, mouse, rat).
http://purl.obolibrary.org/obo/NCBITaxon_9606
Term relations
- monocyte and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and capable of some monocyte chemotaxis and capable of some phagocytosis and capable of some inflammatory response and has high plasma membrane amount some C-C chemokine receptor type 2
- monocyte and capable of some monocyte chemotaxis and capable of some phagocytosis and capable of some inflammatory response and has high plasma membrane amount some C-C chemokine receptor type 2 and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1
- phagocyte
- protein-containing material entity
- monocyte
- lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1
- capable of some inflammatory response
- lacks_plasma_membrane_part some CD19 molecule
- lacks_plasma_membrane_part some CD3 epsilon
- lacks_plasma_membrane_part some CD19 molecule
- lacks_plasma_membrane_part some CD3 epsilon
- has high plasma membrane amount some C-C chemokine receptor type 2
- capable of some monocyte chemotaxis
- lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1