T-helper 17 cell
http://purl.obolibrary.org/obo/CL_0000899
CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive, CXCR3-negative, CCR6-positive, and capable of producing IL-17. [ GOC:add http://www.ncbi.nlm.nih.gov/pubmed/20303875 http://www.ncbi.nlm.nih.gov/pubmed/22343568 http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/20969597 GOC:pam ]
Synonyms: Th17 T-cell, T(H)-17 cell, Th17 CD4+ T cell, Th17 cell, T helper cells type 17, Th17 T lymphocyte, IL-17-producing CD4+ T helper, Th17 T-lymphocyte, helper T cell type 17, Th17 T cell
Term info
- MESH:D058504
human_reference_atlas
This cell type is compatible with the HIPC Lyoplate markers for 'Th17 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 17 T cells.
http://purl.obolibrary.org/obo/NCBITaxon_9606
Term relations
- CD4-positive helper T cell and has part some nuclear receptor ROR-gamma isoform 2 and lacks_plasma_membrane_part some C-X-C chemokine receptor type 3 and has plasma membrane part some C-C chemokine receptor type 6 and capable of some interleukin-17 production