Tc1 cell
http://purl.obolibrary.org/obo/CL_0000917
A CD8-positive, alpha-beta positive T cell that has the phenotype T-bet-positive, eomesodermin-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. [ GOC:pam http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/22343568 GOC:add http://www.ncbi.nlm.nih.gov/pubmed/9914231 ]
Synonyms: Tc1 T lymphocyte, Tc1 T cell, T-cytotoxic T cell type 1, Tc1 CD8+ T cell, CD8-positive Th1 cell, Tc1 T-cell, Th1 non-TFH CD8-positive T cell, Th1 CD8-positive T cell, Tc1 T-lymphocyte
Term info
- BTO:0004888
- BTO:0004793
- FMA:84793
This cell type is compatible with the HIPC Lyoplate markers for 'Tc1 CD8+ T cell', but its logical definition includes additional known characteristics of Tc1 T cells.
Term relations
- CD8-positive, alpha-beta cytokine secreting effector T cell and has part some T-box transcription factor TBX21 and has part some eomesodermin and lacks_plasma_membrane_part some C-C chemokine receptor type 6 and has plasma membrane part some C-X-C chemokine receptor type 3 and capable of some type II interferon production
- CD8-positive, alpha-beta cytokine secreting effector T cell
- has part some eomesodermin
- lacks_plasma_membrane_part some C-C chemokine receptor type 6
- has part some T-box transcription factor TBX21
- has plasma membrane part some C-X-C chemokine receptor type 3
- capable of some type II interferon production