Be1 Cell
http://purl.obolibrary.org/obo/CL_0000943
A Be cell that facilitates development of T-helper 1 (Th1) phenotype in CD4-positive T cells, and secretes high levels of interleukin-2, tumor necrosis factor-alpha and interferon-gamma. [ GOC:dsd http://www.ncbi.nlm.nih.gov/pubmed/11101868 http://www.ncbi.nlm.nih.gov/pubmed/20224569 GOC:msz http://purl.obolibrary.org/obo/go/references/0000031 GOC:tfm ]
Synonyms: B effector 1 cell
Term info
Be1 cells are also reportedly capable of secreting IL-6, IL-10, and IL-12. They are also reportedly CD11b-negative and B220-positive.
B effector cell type 1
Term relations
- Be cell and capable of some type II interferon production and capable of some interleukin-2 production and capable of some tumor necrosis factor production and capable of some positive regulation of T-helper 1 cell differentiation