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small pre-B-II cell

^ http://purl.obolibrary.org/obo/CL_0000954


A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. [ GOC:dsd GOC:rhs GOC:tfm http://www.ncbi.nlm.nih.gov/pubmed/9785673 http://www.ncbi.nlm.nih.gov/pubmed/18432934 http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/16551251 ]

Synonyms: small pre-BII cell

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Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.