large pre-B-II cell

http://purl.obolibrary.org/obo/CL_0000957

A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative. [ http://www.ncbi.nlm.nih.gov/pubmed/9785673 http://www.ncbi.nlm.nih.gov/pubmed/16551251 http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/18432934 GOC:dsd GOC:rhs ]

Synonyms: large pre-BII cell

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Large pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-positive, pre-BCR-positive, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.

has broad synonym

large pre-B cell

Term relations

Equivalent to:

pre-B-II cell and lacks_part some V(D)J recombination-activating protein 1 and lacks_part some V(D)J recombination-activating protein 2 and participates_in some lymphocyte proliferation
pre-B-II cell and participates_in some lymphocyte proliferation and lacks_part some V(D)J recombination-activating protein 1 and lacks_part some V(D)J recombination-activating protein 2

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