T2 B cell
http://purl.obolibrary.org/obo/CL_0000959
A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive. [ http://www.ncbi.nlm.nih.gov/sites/entrez?db=pmc&cmd=search&term=PMC2193793 GOC:dsd http://purl.obolibrary.org/obo/go/references/0000031 GOC:msz http://www.ncbi.nlm.nih.gov/pubmed/12810111 GOC:tfm ]
Synonyms: T2 B-cell, T2 B-lymphocyte, T2 B lymphocyte, transitional stage 2 B cell
Term info
T2 B cells are also reportedly CD20-positive, CD24-positive, CD38-positive, CD48-positive, CD84-positive, CD150-positive, CD244-negative, and CD352-positive.
Term relations
- transitional stage B cell and lacks_plasma_membrane_part some L-selectin and has plasma membrane part some IgD immunoglobulin complex and has plasma membrane part some IgM immunoglobulin complex and has plasma membrane part some complement receptor type 2 and has plasma membrane part some low affinity immunoglobulin epsilon Fc receptor and has plasma membrane part some complement component C1q receptor
- transitional stage B cell
- develops from some T1 B cell
- has plasma membrane part some IgD immunoglobulin complex
- has plasma membrane part some complement component C1q receptor
- has plasma membrane part some low affinity immunoglobulin epsilon Fc receptor
- lacks_plasma_membrane_part some L-selectin
- has plasma membrane part some complement receptor type 2