unswitched memory B cell

http://purl.obolibrary.org/obo/CL_0000970

An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative. [ http://openisbn.com/search.php?q=0781765196&isbn=1/ GOC:dsd http://www.ncbi.nlm.nih.gov/pubmed/22343568 GOC:rhs GOC:add http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/20933013 ]

Synonyms: unswitched memory B lymphocyte, unswitched memory B-cell, unswitched memory B-lymphocyte, non-class-switched memory B cell

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Subsets

human_reference_atlas

comment

This cell type is compatible with the HIPC Lyoplate markers for 'IgD+ memory B cell'. Per DSD: Unswitched memory B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.

has broad synonym

IgD+ memory B cell

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606

Term relations

Equivalent to:

memory B cell and lacks_plasma_membrane_part some IgG immunoglobulin complex and lacks_plasma_membrane_part some IgE immunoglobulin complex and lacks_plasma_membrane_part some IgA immunoglobulin complex and lacks_plasma_membrane_part some syndecan-1 and has plasma membrane part some IgD immunoglobulin complex and has plasma membrane part some IgM immunoglobulin complex and has plasma membrane part some CD27 molecule
memory B cell and has plasma membrane part some IgD immunoglobulin complex and has plasma membrane part some IgM immunoglobulin complex and has plasma membrane part some CD27 molecule and lacks_plasma_membrane_part some IgG immunoglobulin complex and lacks_plasma_membrane_part some IgE immunoglobulin complex and lacks_plasma_membrane_part some IgA immunoglobulin complex and lacks_plasma_membrane_part some syndecan-1

Subclass of:

Related from:

develops_from

class switched memory B cell