CD8_alpha-positive CD11b-negative dendritic cell
http://purl.obolibrary.org/obo/CL_0001000
CD8_alpha-positive CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative and is CD205-positive and CD8_alpha-positive. [ http://purl.obolibrary.org/obo/go/references/0000031 GOC:amm GOC:tfm http://www.ncbi.nlm.nih.gov/sites/entrez?db=pmc&cmd=search&term=PMC2346585 ]
Synonyms: DC.8+
Term info
Cells are defined as having a disposition to secreting inflammatory cytokines. Originally described in the dendritic cell ontology (DC_CL:0000013)(PMID:19243617).
Term relations
- conventional dendritic cell and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some integrin alpha-M and has plasma membrane part some lymphocyte antigen 75 and has plasma membrane part some T-cell surface glycoprotein CD8 alpha chain and capable of some cytokine production and capable of some antigen processing and presentation of exogenous peptide antigen via MHC class I and capable of some positive regulation of inflammatory response
- myeloid leukocyte
- conventional dendritic cell
- has plasma membrane part some T-cell surface glycoprotein CD8 alpha chain
- capable of some positive regulation of inflammatory response
- lacks_plasma_membrane_part some integrin alpha-M
- has plasma membrane part some lymphocyte antigen 75
- capable of some antigen processing and presentation of exogenous peptide antigen via MHC class I
- develops from some pre-conventional dendritic cell
- lacks_plasma_membrane_part some CD4 molecule