CD8-positive, CXCR3-positive, alpha-beta regulatory T cell
http://purl.obolibrary.org/obo/CL_0001041
A CD8-positive alpha-beta-positive T cell with the phenotype CXCR3-positive and having suppressor function. They are capable of producing IL-10, suppressing proliferation, and suppressing IFN-gamma production. [ GOC:dsd http://www.ncbi.nlm.nih.gov/pubmed/19609979 ]
Synonyms: CD8+CXCR3+ T lymphocyte, CD8-positive, CXCR3-positive, alpha-beta regulatory T-cell, CD8+CXCR3+ Treg, CD8-positive, CXCR3-positive, Treg, CD8+CXCR3+ T(reg), CD8+CXCR3+ T-cell, CD8+CXCR3+ T cell, CD8-positive, CXCR3-positive, alpha-beta regulatory T lymphocyte, CD8-positive, CXCR3-positive, alpha-beta regulatory T-lymphocyte, CD8-positive, CXCR3-positive, T(reg)
Term info
These cells may be the human equivalent of murine CD8-positive, CD122-positive alpha-beta regulatory T cell. They are also found in the CD45RA-negative and CD62L-positive fraction.
Term relations
- CD8-positive, alpha-beta regulatory T cell and has part some C-X-C chemokine receptor type 3 and capable of some interleukin-10 production and capable of some negative regulation of type II interferon production and capable of some negative regulation of T cell proliferation