activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell, human
http://purl.obolibrary.org/obo/CL_0001048
A CD4-positive, CD25-positive, CCR4-positive, alpha-beta T regulatory cell with the phenotype HLA-DRA-positive, indicating recent activation. [ GOC:add http://www.ncbi.nlm.nih.gov/pubmed/22343568 ]
Synonyms: activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-cell, activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-lymphocyte, activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T lymphocyte, activated CCR4+ Treg
Term info
This cell type is compatible with the HIPC Lyoplate markers for 'activated CCR4+ Treg'. The inclusion of HLA-DRA in the definition restricts this definition to human activated CD4+ T cells, as activated mouse T cells do not express MHC class II.