activated CD8-positive, alpha-beta T cell, human
A recently activated CD8-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, CCR7-negative, and CD25-positive. [ GOC:add http://www.ncbi.nlm.nih.gov/pubmed/22343568 ]
Synonyms: activated CD8-positive, alpha-beta T-lymphocyte, human, activated CD8-positive, alpha-beta T lymphocyte, human, activated CD8-positive, alpha-beta T-cell, human
Term info
This cell type is compatible with the HIPC Lyoplate markers for 'activated CD8+ T cell', but includes via logical inference from its parent additional markers known to be expressed on activated CD8+ T cells. The inclusion of HLA-DRA in the definition restricts this definition to human activated CD8+ T cells, as activated mouse T cells do not express MHC class II.
activated CD8+ T cell