basophil mast progenitor cell
http://purl.obolibrary.org/obo/CL_0002028
A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa [ http://www.ncbi.nlm.nih.gov/sites/entrez?db=pmc&cmd=search&term=PMC1312421 GOC:ak GOC:tfm GOC:dsd ]
Synonyms: BMCP
Term info
There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low.
https://orcid.org/0000-0003-1980-3228
2010-04-27T12:46:33Z
Term relations
- myeloid lineage restricted progenitor cell and has part some CCAAT/enhancer-binding protein alpha and has part some erythroid transcription factor and has part some endothelial transcription factor GATA-2 and lacks_plasma_membrane_part some high affinity immunoglobulin epsilon receptor subunit alpha and lacks_plasma_membrane_part some transmembrane emp24 domain-containing protein 1 and has plasma membrane part some interleukin-5 receptor subunit alpha and capable of some basophil differentiation and capable of some mast cell differentiation
- granulocytopoietic cell
- protein-containing material entity
- myeloid cell
- capable of some basophil differentiation
- lacks_plasma_membrane_part some transmembrane emp24 domain-containing protein 1
- capable of some mast cell differentiation
- has part some CCAAT/enhancer-binding protein alpha
- has part some erythroid transcription factor
- lacks_plasma_membrane_part some high affinity immunoglobulin epsilon receptor subunit alpha
- has plasma membrane part some interleukin-5 receptor subunit alpha
- develops from some granulocyte monocyte progenitor cell
- has part some endothelial transcription factor GATA-2