type B synovial cell
http://purl.obolibrary.org/obo/CL_0002301
A resident stromal cell located in the synovial membrane and responsible for the production of immune-related cytokines and chemokines. This cell type secretes glycoproteins and hyaluronic acid, has abundant granular endoplasmic reticulum, but contains fewer vacuoles and vesicles. [ https://orcid.org/0000-0002-0819-0473 http://www.ncbi.nlm.nih.gov/pubmed/34772990 http://openisbn.com/search.php?q=0517223651&isbn=1/ GOC:tfm http://www.ncbi.nlm.nih.gov/pubmed/34433485 ]
Synonyms: synovial fibroblast, fibroblast-like synoviocyte
Term info
- BTO:0003652
- FMA:66788
Type B synovial cells play a key role in the pathogenesis of chronic inflammatory diseases, such as rheumatoid arthritis, and are essential for the maintenance of normal joint functions. Fibroblast-like synoviocytes from different joints have different properties, which may contribute to the characteristic pattern of joint involvement in different types of arthritis.
https://orcid.org/0000-0003-1980-3228
2010-09-13T03:39:14Z
Type B synoviocyte
Term relations
- stromal cell
- synovial cell
- produces some synovial fluid
- part of some synovial membrane of synovial joint
- capable of some hyaluronan biosynthetic process