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CD1c-positive myeloid dendritic cell

^ http://purl.obolibrary.org/obo/CL_0002399


A myeloid dendritic cell found in the blood that is CD1c-positive. [ http://www.ncbi.nlm.nih.gov/pubmed/20628149 GOC:dsd GOC:tfm http://www.ncbi.nlm.nih.gov/pubmed/20204387 ]

Term info

Subsets

human_reference_atlas

comment

Normally represent 10-20% of peripheral blood mDCs (human). They are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD285-positive (TLR5), CD286-positive (TLR6), CD288-positive (TLR8), and CD290-positive (TLR10) [PMID:20204387]. Upon TLR stimulation, these cells were potent producers of CXCL8 (IL-8), while producing little TNF-alpha.

contributor

https://orcid.org/0000-0003-1980-3228

creation date

2010-10-04T02:39:01Z

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606