CD4-positive, CD8-intermediate double-positive thymocyte
http://purl.obolibrary.org/obo/CL_0002431
A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD8 co-receptor. [ http://www.immgen.org/index_content.html GOC:tfm ]
Synonyms: T_4+8int_Th, T.4+8int.Th
Term info
https://orcid.org/0000-0003-1980-3228
2010-10-21T02:29:23Z
Term relations
- double-positive, alpha-beta thymocyte and participates_in some positive T cell selection and has plasma membrane part some CD69 molecule and has high plasma membrane amount some alpha-beta T cell receptor complex and has low plasma membrane amount some T cell receptor co-receptor CD8
- double-positive, alpha-beta thymocyte
- develops from some CD69-positive double-positive thymocyte
- participates_in some positive T cell selection
- has low plasma membrane amount some T cell receptor co-receptor CD8
- has plasma membrane part some CD69 molecule
- has high plasma membrane amount some alpha-beta T cell receptor complex