CD14-positive dermal dendritic cell
http://purl.obolibrary.org/obo/CL_0002526
A dermal dendritic cell that is CD1a-negative and CD14-positive. [ http://www.ncbi.nlm.nih.gov/pubmed/20309010 http://www.ncbi.nlm.nih.gov/pubmed/19236899 GOC:dsd ]
Synonyms: CD14+ dermal DC
Term info
They are also CD11c-positive, CD40-positive, CD85j-positive (ILT-2), CD163-positive, CD205-positive (DEC205), CD207-negative (langerin), CD209-positive (DC-SIGN), CD274-positive (PD-L1), CD324-negative (E-cadherin), Factor XIIIa-positive, LOX-I-positive, CLEC6-positive, Dectin-1-positive, and DCIR-positive. Upon stimulation, these cells are capable of producing IL1-beta, IL6, IL8, IL10, IL12p40, IL19, IL20, IL24, TGF-beta, TNF-alpha, GM-CSF, and MCP1. They reside in the dermis.
Term relations
- dermal dendritic cell and lacks_plasma_membrane_part some T-cell surface glycoprotein CD1a and has plasma membrane part some CD14 molecule and capable of some regulation of isotype switching