CD1a-positive dermal dendritic cell

http://purl.obolibrary.org/obo/CL_0002529

A dermal dendritic cell that is CD1a-positive and CD14-negative. [ http://www.ncbi.nlm.nih.gov/pubmed/20309010 GOC:dsd ]

Synonyms: CD1a+ dermal DC

Tree view
Term history

Term info

comment

Reside in the dermis. They are also CD11c-positive, CD40-positive, CD207-negative (langerin), CD209-negative (DC-SIGN), and CD324-negative (E-cadherin). When activated, they are capable of producing CXCL8 (IL-8) and IL-15. Possibly a precursor of Langerhans cells or equivalent of langerin-positive dermal DCs in the mouse.

Term relations

Equivalent to:

dermal dendritic cell and has plasma membrane part some T-cell surface glycoprotein CD1a

Subclass of:

dermal dendritic cell
has plasma membrane part some T-cell surface glycoprotein CD1a