double negative T regulatory cell

http://purl.obolibrary.org/obo/CL_0011024

A double negative thymocyte that is CD3-positive, CD4-negative, CD8-negative, that that are present in the periphery in very low numbers and predominantly produce INF-gamma, TNF-alpha, and a low amount of TGF-beta, but not IL-2, IL-4, IL-10 or IL-13 upon activation. [ http://www.ncbi.nlm.nih.gov/pubmed/16285891 ]

Synonyms: double-negative alpha-beta regulatory T cell, CD4-negative, CD8-negative, alpha-beta regulatory T cells, DN Treg

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https://orcid.org/0000-0001-5208-3432

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Equivalent to:

double negative thymocyte and capable of some negative regulation of immune response

Subclass of:

double negative thymocyte
capable of some negative regulation of immune response