secondary crest myofibroblast
A myofibroblast that is part of an alveoli during alveolarization. The contractile force of this cell elongates the secondary crest, while producing a framework of elastin and tenascin. During the maturation of the septa, secondary crest myofibroblasts, together with matrix fibroblasts, secrete metalloproteinases and other ECM‐remodeling proteins to thin the septal tip ECM. The secondary crest myofibroblast continues producing elastin, eventually undergoing apoptosis during adulthood. [ http://www.ncbi.nlm.nih.gov/pubmed/33624948 http://www.ncbi.nlm.nih.gov/pubmed/31331942 ]
Synonyms: secondary-crest myofibroblast
Term info
https://orcid.org/0000-0001-6677-8489, https://orcid.org/0000-0002-9185-3994
2023-03-16T09:17:47Z
alveolar myofibroblast, SCMFs, SCMF
Term relations
- connective tissue cell
- myofibroblast cell
- participates_in some lung alveolus development
- part of some lung connective tissue