autophagosome assembly
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm. [ http://www.ncbi.nlm.nih.gov/pubmed/9412464 GOC:autophagy ]
Synonyms: autophagosome biosynthesis, autophagosome formation, autophagic vacuole assembly
Term info
autophagic vacuole formation
PAS formation
biological_process
GO:0000045
Term relations
- organelle assembly
- autophagosome organization
- has part some Atg12 conjugating enzyme activity
- results_in_assembly_of some autophagosome
- has part some Atg12 activating enzyme activity
- has part some Atg8-specific peptidase activity
- has part some Atg12 ligase activity
- starts with some Atg1/ULK1 kinase complex assembly