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B-1 B cell differentiation

^ http://purl.obolibrary.org/obo/GO_0001923


The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. [ GOC:add http://openisbn.com/search.php?q=0781735149&isbn=1/ ]

Synonyms: B-1 B-lymphocyte differentiation, B-1 B lymphocyte differentiation, B-1 B-cell differentiation