transmembrane signaling receptor activity

http://purl.obolibrary.org/obo/GO_0004888

Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. [ http://en.wikipedia.org/wiki/Transmembrane_receptor GOC:go_curators ]

Synonyms: transmembrane signalling receptor activity

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Term history

Term info

database cross reference

Reactome:R-HSA-193672 (Sphingomyelinase is activated by the NGF:p75NTR complex)

comment

This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.

has alternative id

GO:0099600, GO:0004926

has broad synonym

transmembrane receptor activity

has obo namespace

molecular_function

GO:0004888

Term relations

Subclass of:

signaling receptor activity