iron ion transmembrane transporter activity
http://purl.obolibrary.org/obo/GO_0005381
Enables the transfer of iron (Fe) ions from one side of a membrane to the other. [ GOC:ai ]
Synonyms: iron transporter activity, iron cation channel activity, iron channel activity, transmembrane iron ion permease activity, transmembrane iron permease activity
Term info
- Reactome:R-HSA-904830 (SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region)
- Reactome:R-HSA-5623558 (Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol)
- Reactome:R-HSA-917936 (MCOLN1 transports Fe2+ from endosome lumen to cytosol)
- Reactome:R-HSA-5655733 (Defective SLC40A1 does not transport Fe2+ from cytosol to extracellular region)
- Reactome:R-HSA-435349 (SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol)
An example of this is mouse ferroportin (UniProtKB:Q9JHI9), which transports iron out of the cell.
zinc, iron permease activity, multicopper ferroxidase iron transport mediator activity
GO:0097689, GO:0005382, GO:0016033
molecular_function
GO:0005381
https://github.com/geneontology/go-ontology/issues/17162
Term relations
- transition metal ion transmembrane transporter activity
- part of some iron ion transmembrane transport
- has primary input some iron cation