G protein-coupled receptor signaling pathway
http://purl.obolibrary.org/obo/GO_0007186
The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [ http://www.ncbi.nlm.nih.gov/pubmed/24568158 http://en.wikipedia.org/wiki/G_protein-coupled_receptor http://www.ncbi.nlm.nih.gov/pubmed/16902576 GOC:bf GOC:mah ]
Synonyms: G-protein coupled receptor protein signaling pathway, G-protein coupled receptor protein signal transduction, GPCR signalling pathway, G protein coupled receptor protein signaling pathway, GPCR signaling pathway, G protein coupled receptor protein signalling pathway, G-protein coupled receptor signalling pathway, G-protein-coupled receptor protein signalling pathway
Term info
goslim_drosophila
GO:0038042
G-protein coupled receptor signaling pathway via GPCR dimer, dimeric G-protein coupled receptor signaling pathway, dimeric G-protein coupled receptor signalling pathway
biological_process
GO:0007186