JSON

programmed cell death

^ http://purl.obolibrary.org/obo/GO_0012501


A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. [ GOC:mtg_apoptosis GOC:lr ]

Term info

Subsets

goslim_chembl, goslim_generic, goslim_drosophila, prokaryote_subset, goslim_agr, goslim_mouse, goslim_plant

comment

Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children.

has related synonym

caspase-independent apoptosis, PCD, RCD

has alternative id

GO:0016244

has broad synonym

regulated cell death

has narrow synonym

non-apoptotic programmed cell death, nonapoptotic programmed cell death, caspase-independent cell death

has obo namespace

biological_process

id

GO:0012501

imported from

http://purl.obolibrary.org/obo/cl.owl

term tracker item

https://github.com/geneontology/go-ontology/issues/24835