bilirubin transmembrane transporter activity
Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile. [ GOC:ai http://openisbn.com/search.php?q=0198547684&isbn=1/ ]
Term info
- Reactome:R-HSA-5679041 (ABCC2 transports BMG,BDG from cytosol to extracellular region)
- Reactome:R-HSA-9661417 (ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region)
- Reactome:R-HSA-5679031 (Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region)
molecular_function
GO:0015127
Term relations
- carboxylic acid transmembrane transporter activity
- part of some bilirubin transport
- has primary input some bilirubin(2-)