The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. [ GOC:jl http://openisbn.com/search.php?q=0198506732&isbn=1/ http://openisbn.com/search.php?q=0192801023&isbn=1/ ]