negative regulation of isotype switching
Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching. [ GOC:go_curators ]
Synonyms: negative regulation of isotype switch recombination, down-regulation of isotype switching, down regulation of isotype switching, negative regulation of class switch recombination, downregulation of isotype switching, negative regulation of class switching
Term info
inhibition of isotype switching
biological_process
GO:0045829
Term relations
- negative regulation of B cell activation
- negative regulation of immunoglobulin production
- regulation of isotype switching
- negative regulation of immunoglobulin mediated immune response
- negative regulation of DNA recombination
- negative regulation of developmental process
- negatively regulates some isotype switching