JSON

Atg1/ULK1 kinase complex

^ http://purl.obolibrary.org/obo/GO_1990316

A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation. [ http://www.ncbi.nlm.nih.gov/pubmed/15743910 GOC:rb http://www.ncbi.nlm.nih.gov/pubmed/19597335 http://www.ncbi.nlm.nih.gov/pubmed/19258318 http://www.ncbi.nlm.nih.gov/pubmed/22885598 GOC:DOS GOC:bhm http://www.ncbi.nlm.nih.gov/pubmed/19211835 ]

Synonyms: ULK complex, ULK1 signaling complex, ULK1 complex, Atg1p signalling complex, ATG1-ATG13 complex, ULK1-ATG13-FIP200 complex, ATG1 kinase complex, ATG1/ULK1 signaling complex, autophagy-initiation complex, ULK1-ATG13-RB1CC1 complex

Term info

creation date

2014-03-14T10:55:11Z

has alternative id

GO:0034273, GO:0070969

has obo namespace

cellular_component

id

GO:1990316