Term info
alternative label
cell culture passaging
comment
An active cell culture is typically split when it has grown to confluence in its culture dish. Cell culture splitting of a cell culture sample results in an increase in its passage number, which measures how long a sample has been propagated in vitro, and therefore how many selective or genetic changes it is likely to have undergone.
definition source
OBI branch derived
editor preferred term
cell culture splitting
example of usage
The act of taking a cell culture of high density, counting the cells, removing part of the cells, and re-seeding a select number of the cells into new flasks with fresh tissue culture media.
has curation status
http://purl.obolibrary.org/obo/IAO_0000125
imported from
http://purl.obolibrary.org/obo/obi.owl
term editor
PlanAndPlannedProcess Branch