extravillous trophoblast
The outermost layer of trophoblast, produced by cytotrophoblast where there is direct contact with maternal decidua rather than blood. The EVT cells travel into the decidua, reacting with NK cells and invading maternal blood vessels feeding the placenta, softening the walls and replacing the lining with fetal tissue, a process called conversion. [ BTO:0002366 ]
Synonyms: intermediate trophoblast
Term info
- BTO:0002366
- FMA:86561
interstitial trophoblast
uberon
UBERON:0000426
Intermediate trophoblast