JSON

pronephros

^ http://purl.obolibrary.org/obo/UBERON_0002120

In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. [ http://amigo.geneontology.org/amigo/term/GO:0048793 http://en.wikipedia.org/wiki/Pronephros ]

Synonyms: pronephric kidney

Term info

database cross reference
  • MESH:D060910
  • TAO:0000151
  • BTO:0001541
  • NCIT:C34280
  • EHDAA:1017
  • EMAPA:16579
  • MAT:0000117
  • EHDAA2:0001570
  • EFO:0000927
  • UMLS:C0231048 (ncithesaurus:Pronephros)
  • ZFA:0000151
  • Wikipedia:Pronephros
  • SCTID:308804007
  • VHOG:0000037
  • AAO:0011089
  • FMA:72170
  • MIAA:0000117
  • XAO:0002000
Subsets

uberon_slim, efo_slim, organ_slim

UBPROP 0000001

A kidney formed of nephric tubules arising in the anterior region of the nephric ridge; forms only as a transient embryonic structure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.748][VHOG], Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.[AAO], The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.Kimmel et al, 1995.[TAO]

UBPROP 0000003

In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]

UBPROP 0000007

pronephric

comment

Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104

has related synonym

embryonic kidney, archinephron, pronephron

has alternative id

UBERON:0005794

id

UBERON:0002120

prefLabel

Pronephros