JSON

subcommissural organ

^ http://purl.obolibrary.org/obo/UBERON_0002139

The subcommissural organ is a circumventricular organ consisting of ependymal and hypendymal cells which secrete SCO-spondin[WP,partially vetted]. [ http://en.wikipedia.org/wiki/Subcommissural_organ http://www.ncbi.nlm.nih.gov/pubmed/9579598 ]

Term info

database cross reference
  • DHBA:12101
  • UMLS:C0038533 (BIRNLEX:1028)
  • MA:0002941
  • DMBA:16514
  • BIRNLEX:1028
  • FMA:72414
  • Wikipedia:Subcommissural_organ
  • EMAPA:35828
  • SCTID:369193006
  • ZFA:0000683
  • BAMS:SCO
  • CALOHA:TS-0986
  • neuronames:483 (BIRNLEX:1028)
  • HBA:9489
  • GAID:794
  • TAO:0000683
  • BTO:0001820
  • MESH:D013351
Subsets

uberon_slim, pheno_slim, vertebrate_core

comment

Occurs throughout the vertebartes [PMID:9579598, DOI:10.1002/ar.1091260210]. First appears in hagfish(Olsson). In many species, including the human, it reaches its full development during embryonic life[PMID:9579598]. During the course of phyletic evolution, one notes various changes. Indeed, in lower vertebrates, the SCO presents a greater degree of enzyme activity than the ependyma while in birds the ependyma demonstrates a more intense activity than the SCO[PMID:479574] Sometimes preceded by flexural organ[DOI:10.1007/BF00303086]. Hypendymal cells are rare in non-mammals [PMID:9579598].

curator note

Hypendymal cells being part of the subcommissural organ is not axiomatized as it is rare in non-mammals. Consider using GCIs if this axiom needs to be added.

depicted by

http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray715.png

has related synonym

cerebral aqueduct subcommissural organ, dorsal subcommissural organ, organum subcommissurale, corpus subcommissurale, SCO

id

UBERON:0002139

prefLabel

Subcommissural organ

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_7742