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locus ceruleus

^ http://purl.obolibrary.org/obo/UBERON_0002148


The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]. [ GAID:577 http://en.wikipedia.org/wiki/Locus_ceruleus http://amigo.geneontology.org/amigo/term/GO:0021703 ]

Synonyms: blue nucleus, locus caeruleus, locus coeruleu, nucleus pigmentosus pontis, caerulean nucleus, Noradrenergic cell group A6, nucleus caeruleus, locus coeruleus, nucleus of locus caeruleus, substantia ferruginea

Term info

database cross reference
  • UMLS:C0023951 (BIRNLEX:905)
  • BTO:0001408
  • ZFA:0000539
  • MA:0001017
  • FMA:72478
  • Wikipedia:Locus_ceruleus
  • BIRNLEX:905
  • EFO:0001963
  • EMAPA:35502
  • DMBA:16972
  • NCIT:C97333
  • UMLS:C0023951 (ncithesaurus:Locus_Coeruleus)
  • TAO:0000539
  • MBA:147
  • MESH:D008125
  • HBA:9148
  • GAID:577
  • BAMS:LC
  • SCTID:369016004
  • BAMS:CAE
  • BM:Pons-LC
  • neuronames:583 (BIRNLEX:905)
  • DHBA:12819
Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core

plural term
loci coeruleus [ ZFA:0000539 ]

RO 0002171

http://purl.obolibrary.org/obo/UBERON_0002587, http://purl.obolibrary.org/obo/UBERON_0003004, http://purl.obolibrary.org/obo/UBERON_0002267, http://purl.obolibrary.org/obo/UBERON_0002047

depicted by

http://upload.wikimedia.org/wikipedia/commons/7/77/Gray709.png

editor note

TODO - check ZFA/pons. also GO says part of dorsorostral pons

has related synonym

locus cinereus, locus coeruleus (Vicq d'Azyr), loci coeruleus, nucleus loci caerulei

id

UBERON:0002148

prefLabel

locus ceruleus, Locus ceruleus